If Indianapolis has ever produced any music worth mentioning, I don't know about it. John "Cougar" Mellencamp is the only guy I know of from Indiana, period, but he's from some other city. Or "Small Town", as it were. Jacksonville was the home of Southern rock titans Lynyrd Skynyrd and also-rans Molly Hatchet in the 70s, and several members of the Allman Brothers Band hail from there. But other than that it has a pretty dubious musical heritage, including being the birthplace of Pat Boone and, more recently, home of the odious Limp Bizkit, who apparently took their spelling cues from local heroes Skynyrd.
Houston, on the other hand, is all about the fifth ward, which has a hiphop history stretching all the way back to what Ice Cube termed "the trigger-happy, motherfuckin' Geto Boys", and carries though to today's Swishahouse crew, making Houston, along with with New Orleans and Atlanta, one of the capitals of Dirty South hiphop. Boo-yah.
And if I have to tell you what kind of music comes from Nashville, well... you do know what "music" is, right?